Senator John McCain passed away Saturday. He was 81. McCain's family announced Friday the senator had stopped treatment for his brain cancer.

McCain was with his wife Cindy and their family when he passed in the afternoon, the statement said.

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"My heart is broken. I am so lucky to have lived the adventure of loving this incredible man for 38 years," said Cindy McCain in a tweet. "He passed the way he lived, on his own terms, surrounded by the people he loved, in the the place he loved best."

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Senator Richard Burr (R-NC) released the following statement on the passing of Senator John McCain (R-AZ): “I am deeply saddened by the passing of my friend and colleague, John McCain. John was a true patriot, who placed his duty to his family and his country above all else. He faced this battle, which would be his last, with the courage that defined his career and the grace that comes from a life well-lived. He will be remembered as he hoped to be remembered: as a man who served his country with honor. Brooke and I are grateful for his service, and send our prayers to Cindy and the entire McCain family.”

Senator Thom Tillis issued the following statement on the passing of Senator John McCain: “America has lost John McCain – a true titan of the Senate who was one of our nation’s greatest war heroes and public servants. He will be long remembered for his principled leadership, courage, grit, and always putting country first. “It was an honor to call John McCain a friend and serve alongside him in the Senate, especially on the Armed Services Committee where he acted as a mentor to myself and the other members. “Susan and I are deeply saddened by John’s passing, and we send our condolences to Cindy and the McCain family, who have demonstrated incredible grace and strength during this difficult time.”

Congresswoman Alma S. Adams, Ph.D. (NC-12) released the following statement on the passing of Senator John McCain (R-AZ): “Senator John Sidney McCain, III was a true statesman,” said Congresswoman Adams. “His love and devotion to our country and for his family is admired by all. I have always respected his decency, integrity, and love for humanity. We are forever grateful for his sacrifice and stalwart leadership, both on the battlefield and in elected office. My prayers are with his wife Cindy and the entire McCain family. We stand with you in mourning the loss of an American hero.”

Rep. Mark Walker tweeted this about McCain:

Rep. Ted Budd:

President Donald Trump tweeted sympathies to the McCain family

Wake Forest University remembers John McCain who delivered the commencement address for the class of 2002: Sen. John McCain impressed a timeless and personal theme upon Wake Forest University’s Class of 2002 when he delivered the commencement address: “It is courage that counts.” See Full speech here: Click on John McCain, Wake Forest University 2002

RELATED | McCain Urged Wake Forest Grads To Have Courage

U.S. Sen. Mark R. Warner (D-VA) issued the below statement on the passing of U.S. Sen John McCain (R-AZ): "We lost a hero tonight. John McCain served this country with honor, purpose and courage for his entire life, regardless of the personal cost. He was a giant of the Senate. His service, sacrifice and patriotism should be an inspiration to every American. "My heart goes out to Cindy and the entire McCain family. The prayers of a grateful nation are with them during this difficult time."

Former president Barack Obama tweeted this statement:

Former Senator and Presidential candidate Hillary Clinton tweeted this about John McCain:

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